The San Francisco 49ers are a 9.5 point underdog against the Green Bay Packers and most of the free world figures Green Bay at least wins Cheap DeForest Buckner Jersey , even if they don’t cover the spread. There are a few holdouts among Week 6 NFL picks, including SB Nation’s own Ryan Van Bibber. His reasoning for picking the 49ers? “The Packers really should beat the 49ers on Monday night, but, hey, I’m not getting burned by them again.”There’s a website called NFL Pick Watch that tracks picks from NFL analysts, be they experts or slightly better than amateurs. They have 113 people they track, and of the ones who have submitted a pick, 98 percent are picking the Packers. The two people picking the 49ers are RVB and CBS Sports’ Jason La Canfora.Given the Buffalo Bills beat the Minnesota Vikings in Minneapolis, it is safe to say that a 49ers upset is possible. It is not likely, but the NFL is proving this year that upsets can easily happen even amongst the worst teams in the league.But what will it take for the 49ers to spring an upset in Lambeau? If the 49ers don’t turn the ball over five times and can get one or two takeaways, it would put them in a much better position. But it will take more than that. Winning the turnover battle will help, but they’ll need more than that. They can’t have six drops, they can’t regularly miss tackles on defense, they certainly can’t be missing extra points!On offense, the 49ers will have to hold up against Mike Pettine’s exotic blitzing. Mike McGlinchey has improved in pass coverage the past couple weeks, and he’ll need to continue that this week. It’d be great having Matt Breida playing, but if not, they will turn to Alfred Morris to grind some clock. He has gotten more work in the passing game, but dominating time of possession (and not turning the ball over) will be key.On defense, the 49ers absolutely need to get pressure against a limited Rodgers. He still can get his passes off as quick as anybody, but with knee issues , it is critical the 49ers make him uncomfortable. On the back-end, they need whomever starts opposite Richard Sherman to show up with something resembling a decent performance.The 49ers don’t need a perfect game to beat Green Bay, but they do need a fundamentally sound game. I agree with Shanahan’s specific criticisms of Grant Cohn’s discipline questions, but I do think fundamentals have been a problem for this team. We have seen improvement, but the problem is inconsistency. The team improved their tackling this past week, only to struggle in a big way with drops. They cannot afford any inconsistency given the injuries that have left them shorthanded.I know most everybody thinks the 49ers will lose this game, but if they were to spring the upset, how do you see it playing out? I’m not expecting a full-on game recap, but what are some of the big things that lead to the upset?49ers have decision to make with suspended WR Victor Bolden in Week 5 Fooch’s update: The 49ers have a week to decide, so can wait until after the Cardinals game if they want.The San Francisco 49ers have an assortment of injury issues, and head coach Kyle Shanahan said they might have to look at bringing in some healthy bodies at various positions.While they figure out who to bring in for Tuesday workouts, the 49ers have a decision to make with regard to wide receiver Victor Bolden. Over the summer, the NFL suspended Bolden for four games due to a violation of the league’s policy on performance-enhancing substances. He was allowed to take part in training camp and the preseason, but the 49ers then placed him on the Reserve/Suspended list as they cut down to 53 players.Bolden’s suspension is over, and the team has until Wednesday to figure out what to do. He currently does not count against the 53-man roster, and the 49ers get a two-day exemption to figure out if they want to release a player to make room for Bolden, or release Bolden to free agency.A year ago, Bolden spent the first 13 games of the season on the 53-man roster, and the final three games on injured reserve. In his 13 games on the roster, Bolden was active for nine games and inactive for four games. He was primarily a special teams player, appearing in 122 special teams snaps and 27 offensive snaps. He was the team’s starting kick returner , with 19 returns for 396 yards (20.8 yards per return).The 49ers held onto him through the suspension, and while there was nothing lost in keeping him around, it does suggest they might have a spot for him on the roster. At the time of the suspension announcement, Bolden said he unknowingly used a supplement on the NFL’s banned substance list. He acknowledged needing to take full responsibility for not verifying the ingredients of the supplement, and the 49ers seemed to accept that it was an unintentional mistake.D.J. Reed is currently the team’s starting kick returner, averaging 30.3 yards per return on nine kickoffs. The rules have changed in terms of the kick coverage players being delayed getting down the field, but Reed is fourth in return average, so he’s finding success in the role.There are currently six wide receivers on the depth chart: Pierre Gar莽on, Marquise Goodwin, Trent Taylor, Dante Pettis, Kendrick Bourne, and Richie James. Through four games, James has been active once, playing seven offensive snaps and no special teams snaps.If the 49ers want Bolden back on the roster, my guess is they would release James in hopes he gets through waivers and they can sign him to the practice squad. James was an explosive option in the preseason, but has not been able to earn a spot on the game-day roster aside from the one game active when Marquise Goodwin was hurt.The 49ers have two days to make a decision, and I suspect any roster move does not formally happen until Wednesday.